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Lemmon 714 is a sedative and hypnotic medication. It was sold under the brand names Quaalude and Sopor among others and sold as a combination drug under the brand name Mandrax which contained 300 mg methaqualone and 25mg diphenhydramine within the same tablet. Commercial production of methaqualone was halted due to widespread abuse and addictiveness. It is a member of the quinazolinone class.
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Methaqualone, sold under the brand name Quaalude in the US and Mandrax in the UK and South Africa, is a sedative and hypnotic medication. It is a member of the Quinazolinone class. The sedative-hypnotic activity of methaqualone was first noted by researchers in the 1950s. In 1962, methaqualone was patented in the US by Wallace and Tiernan. Its use peaked in the early 1970s as a hypnotic, for the treatment of insomnia, and as a sedative and muscle relaxant.
By 1965, it was the most commonly prescribed sedative in Britain, where it has been sold legally under the names Malsed, Malsedin, and Renoval. In 1965, a methaqualone/antihistamine combination was sold as the sedative drug Mandrax, by Roussel Laboratories (now part of Sanofi-Aventis). In 1972, it was the sixth-bestselling sedative in the US, where it was legal under the brand name Quaalude. Quaalude in the United States was originally manufactured in 1965 by the Fort Washington, Pennsylvania, based pharmaceutical firm William H. Quaaludes for sale here.